Fallout 3 troque la vue de haut des deux premiers épisodes pour adopter un environnement post apocalyptique en 3D plus grand et complexe. Ce jeu de rôle sur Xbox 360 offre une grande liberté d'action au joueur qui pourra faire évoluer son personnage comme bon lui semble mais surtout interagir avec les autres protagonistes comme il le souhaite pour aboutir sur l'une des 200 fins différentes.
She gave my mother such a turn, that I have always been convinced I am indebted to Miss Betsey for having been born on a Friday. The word was appropriate to the moment. My mother was so much worse that Peggotty, coming in with the teaboard and candles, and seeing at a glance how ill she was, - as Miss Betsey might have done sooner if there had been light enough, - conveyed her upstairs to her own room with all speed; and immediately dispatched Ham Peggotty, her nephew, who had been for some days past secreted in the house, unknown to my mother, as a special messenger in case of emergency, to fetch the nurse and doctor.