BioShock 2 est un jeu de tir à la première personne sur Xbox 360. Il se déroule 10 ans après le premier jeu et vous fait incarner un Protecteur. En tant que tel, vous devez traverser les rues de Rapture, la cité engloutie, et tenter d'obtenir enfin votre liberté. Pour y parvenir, vous devrez affronter de nombreux ennemis et prendre des décisions qui affecteront le sort de la ville toute entière. Mais la grande nouveauté de cet épisode tient à l'apparition d'un mode multi pour 10 participants.
She gave my mother such a turn, that I have always been convinced I am indebted to Miss Betsey for having been born on a Friday. The word was appropriate to the moment. My mother was so much worse that Peggotty, coming in with the teaboard and candles, and seeing at a glance how ill she was, - as Miss Betsey might have done sooner if there had been light enough, - conveyed her upstairs to her own room with all speed; and immediately dispatched Ham Peggotty, her nephew, who had been for some days past secreted in the house, unknown to my mother, as a special messenger in case of emergency, to fetch the nurse and doctor.