Banjo-Tooie sur Nintendo 64 est le deuxième volet des aventures de l'ours débonnaire et l'oiseau cynique, toujours orienté plates-formes. Terrassée lors du premier épisode, la sorcière Gruntilda n'importune plus la Montagne Spirale. Le monde vit paisiblement mais c'est sans compter sur les deux soeurs de Gruntilda qui sont bien décidées à la ressusciter. Les deux soeurs s'échappent en détruisant la maison de Banjo et en tuant Bottles, son ami. La vengeance commence...
She gave my mother such a turn, that I have always been convinced I am indebted to Miss Betsey for having been born on a Friday. The word was appropriate to the moment. My mother was so much worse that Peggotty, coming in with the teaboard and candles, and seeing at a glance how ill she was, - as Miss Betsey might have done sooner if there had been light enough, - conveyed her upstairs to her own room with all speed; and immediately dispatched Ham Peggotty, her nephew, who had been for some days past secreted in the house, unknown to my mother, as a special messenger in case of emergency, to fetch the nurse and doctor.